基因名：
PPIL1
产品别名：
CGI-124； CYPL1； PCH14； PPIase； hCyPX； PPIL1； peptidylprolyl isomerase like 1； peptidylprolyl isomerase like 1； peptidyl-prolyl cis-trans isomerase-like 1； cyclophilin like 1； cyclophilin-related gene 1； peptidyl-prolyl cis-trans isomerase； peptidylprolyl isomerase (cyclophilin)-like 1； rotamase PPIL1； 亲环素相关蛋白1；
背景信息：
Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ,skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.
