基因名:
RXFP3
产品别名:
GPCR135; RLN3R1; RXFPR3; SALPR; RXFP3; relaxin family peptide receptor 3; relaxin family peptide receptor 3; relaxin-3 receptor 1; G-protein coupled receptor GPCR135; G-protein coupled receptor SALPR; RLN3 receptor 1; g protein-coupled receptor SALPR; relaxin/insulin like family peptide receptor 3; somatostatin and angiotensin-like peptide receptor; G蛋白偶联受体135/松弛素受体3; 松弛素/胰岛素样肽受体3(RXFP3);
背景信息:
Relaxin Receptor 3 is a G protein-coupled receptor that binds Relaxin 3 and influences differentiation and maintenance of the nervous system. Relaxin Receptor 3 shares sequence similarity with somatostatin receptors and angiotensin receptors. It mediates central processing of sensory signals in the rat and is thought to be a modulator of stress responses. Relaxin Receptor 3 is present in the brain, with highest expression in substantia nigra and pituitary, followed by hippocampus, spinal cord, amygdala, caudate nucleus and corpus callosum, and low level expression in cerebellum. In peripheral tissues there are high levels in adrenal glands and low levels in pancreas, salivery gland, placenta, mammary gland and testis.