基因名:
Ing5
产品别名:
CG9293; Dmel\CG9293; Ing5; Inhibitor of growth family member 5; Inhibitor of growth family member 5; inhibitor of growth family member 5; CG9293-PA; CG9293-PB; Ing5-PA; Ing5-PB; 生长抑制蛋白5;
背景信息:
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway. [provided by RefSeq, Jul 2008]