基因名:
Usp30
产品别名:
CG3016; Dmel\CG3016; Q9W462; USP30; dUSP30; Usp30; Ubiquitin specific protease 30; Ubiquitin specific protease 30; ubiquitin specific protease 30; CG3016-PA; CG3016-PB; Usp30-PA; Usp30-PB; ubiquitin specific peptidase 30;
背景信息:
USP30(57-517) contains the catalytic domain of USP30 with the N-terminal membrane bound domain being deleted. USP30 deubiquitinates substrates of Parkin including MIRO1, TOMM20, MFN1, and MFN2 on mitochondrial membranes and functions to suppress mitophagy. It prefers cleavage of K6- and K11-linked polyubiquitin chains.