基因名:
LRP12
产品别名:
MIG13A; ST7; LRP12; LDL receptor related protein 12; LDL receptor related protein 12; low-density lipoprotein receptor-related protein 12; LDLR-related protein 12; suppressor of tumorigenicity 7 protein; 低密度脂蛋白受体相关蛋白12; 低密度脂蛋白受体相关蛋白12(LRP12);
背景信息:
Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 contains 2 CUB domain and 5 LDL-receptor class A domain. LRP12 has been shown to interact with GNB2L1, ZFYVE9 and ITGB1BP3. LRP12 is a receptor probably, which may be involved in the internalization of lipophilic molecules and/or signal transduction. In addition, LRP12 may act as a tumor suppressor.