基因名：
TBK1
产品别名：
FTDALS4； IIAE8； NAK； T2K； TBK1； TANK binding kinase 1； TANK binding kinase 1； serine/threonine-protein kinase TBK1； NF-kB-activating kinase； NF-kappa-B-activating kinase； NF-κB活化激酶； NF-κB活化激酶蛋白； TANK结合激酶1(TBK1)； 磷酸化NF-κB活化激酶； 钙粘蛋白相关蛋白CTNNA3；
背景信息：
The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors. The protein is also an important kinase for antiviral innate immunity response. [provided by RefSeq, Sep 2021]
