基因名:
IL17B
产品别名:
IL-17B; IL-20; NIRF; ZCYTO7; IL17B; interleukin 17B; interleukin 17B; interleukin-17B; cytokine-like protein ZCYTO7; interleukin 20; interleukin-17 beta; neuronal interleukin-17 related factor; 白介素-17B; 白介素17B(IL17B);
背景信息:
Interleukin-17B (IL-17B) is a member of IL-17 cytokines family that plays important roles in host defence responses and inflammatory diseases. In addition to IL-17B, members of the IL-17 family include IL-17A, IL-17C, IL-17D, IL-17E and IL-17F. The six IL-17 cytokines are highly conserved at C terminus, and contain five spatially conserved cysteine residues that mediate dimerization. Expression of IL-17B protein has been reported in neurons, testis, ovary, stomach, pancreas, small intestine and chondrocytes. IL-17B binds to Interleukine-17 receptor B (IL-17 RB) and induces the production of inflammatory cytokines and the infiltration of inflammatory immune cells.