基因名：
DKK3
产品别名：
CRRL； REIC； RIG； DKK3； dickkopf WNT signaling pathway inhibitor 3； dickkopf WNT signaling pathway inhibitor 3； dickkopf-related protein 3； RIG-like 5-6； RIG-like 7-1； cardiomyocyte regeneration-related lncRNA； dickkopf 3 homolog； dickkopf homolog 3； dickkopf-3； dkk-3； hDkk-3； regulated in glioma； Dickkopf相关蛋白3(DKK3)； 抑癌蛋白DKK3；
背景信息：
Dickkopf-related protein 3 (DKK3) belongs to the DKK protein family including Dkk-1, 2, 3 and -4. DKK3 is a 350 amino acid secreted glycoprotein which is comprised of an N-terminal signal peptide and 2 conserved cysteine-rich domains that are separated by a 12 amino acid linker region. Dkk-3 also have one prokineticin domain. DKK3 is involved in embryonic development through its inhibition of the WNT signaling pathway. The Dkk family also includes Soggy, which is homologous to Dkk-3 but not to the other family members. Soggy has not been shown to inhibit Wnt signaling, and its role in the pathway is unclear.
