基因名：
Polk
产品别名：
DINP； Dinb1； Polk； polymerase (DNA directed), kappa； polymerase (DNA directed), kappa； DNA polymerase kappa； DINB protein； DNA damage-inducible protein b； DNA-directed DNA polymerase kappa； DinB homolog 1； DNA聚合酶κ/DNA polκ；
背景信息：
This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients. [provided by RefSeq, Sep 2016]
