基因名：
CNNM3
产品别名：
ACDP3； CNNM3； cyclin and CBS domain divalent metal cation transport mediator 3； cyclin and CBS domain divalent metal cation transport mediator 3； metal transporter CNNM3； ancient conserved domain protein 3； ancient conserved domain-containing protein 3； cyclin-M3； 周期素M3；
背景信息：
Cyclin M3 is a 707 amino acid multi-pass membrane protein that shares weak sequence similarity with cyclin proteins, yet displays no cyclin-like function in vivo. Though ubiquitously expressed, Cyclin M3 is found at highest levels in kidney, brain, spleen and heart. Cyclin M3 is localized to the nucleus where it is likely a metal transporter. Cyclin M3 contains two CBS domains, which appear to bind ligands with an adenosyl group such as AMP, ATP and S-AdoMet and may play a regulatory role in sensitizing proteins to adenosyl-carrying ligands. There are three isoforms of Cyclin M3 that are produced as a result of alternative splicing events.
