基因名：
HSPB8
产品别名：
CMT2L； DHMN2； E2IG1； H11； HMN2； HMN2A； HSP22； HSPB8； heat shock protein family B (small) member 8； heat shock protein family B (small) member 8； heat shock protein beta-8； E2-induced gene 1 protein； alpha-crystallin C chain； heat shock 22kDa protein 8； heat shock 27kDa protein 8； protein kinase H11； small stress protein-like protein HSP22； 热休克蛋白-22； 热休克蛋白β8(HSPb8)；
背景信息：
Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity，appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
