基因名:
LRRTM2
产品别名:
LRRTM2; leucine rich repeat transmembrane neuronal 2; leucine rich repeat transmembrane neuronal 2; leucine-rich repeat transmembrane neuronal protein 2; leucine-rich repeat neuronal 2 protein; leucine-rich repeat transmembrane neuronal 2 protein; 富含亮氨酸重复跨膜神经元蛋白2;
背景信息:
Leucine-Rich Repeat Transmembrane Neuronal Protein 2 (LRRTM2) is a single-pass type I membrane protein that belongs to the LRRTM family. It contains ten LRR (leucine-rich) repeats, one LRRCT domain, and one LRRNT domain. LRRTM2 is expressed in neuronal tissues, and it interacts with DLG4 and NRXN1. LRRTM2 has been suggested to be involved in the development and maintenance of excitatory synapses in the vertebrate nervous system. LRRTM2 also regulates the surface expression of AMPA receptors. LRRTM2 acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B.