基因名:
TKFC
产品别名:
DAK; NET45; TKFCD; TKFC; triokinase and FMN cyclase; triokinase and FMN cyclase; triokinase/FMN cyclase; ATP-dependent dihydroxyacetone kinase; DHA kinase; Dha kinase/FMN cyclase; FAD-AMP lyase cyclic FMN forming; FAD-AMP lyase cyclizing; bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing); dihydroxyacetone kinase 2 homolog; glycerone kinase; testis tissue sperm-binding protein Li 84P; 二羟基丙酮激酶;
背景信息:
DAK is a 575 amino acid protein belonging to the dihydroxyacetone kinase (DAK) family. Existing as a homodimer, DAK catalyzes the formation of FAD to cyclin FMN, as well as the phosphorylation of dihydroxyacetone and splitting of ribonucleoside diphosphate-X compounds. DAK contains one DhaK domain, a DhaL domain, and is encoded by a gene located on human chromosome 11. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.