重组Ras蛋白特异鸟嘌呤核苷酸释放因子3

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重组磷酸化Ras蛋白特异鸟嘌呤核苷酸释放因子3
Recombinant RASGRP3

基因名：

RASGRP3

产品别名：

GRP3； RASGRP3； RAS guanyl releasing protein 3； RAS guanyl releasing protein 3； ras guanyl-releasing protein 3； CalDAG-GEFIII； RAS guanyl releasing protein 3 (calcium and DAG-regulated)； calcium and DAG-regulated guanine nucleotide exchange factor III； calcium- and diacylglycerol-regulated guanine nucleotide exchange factor III； guanine nucleotide exchange factor for Rap1； Ras蛋白特异鸟嘌呤核苷酸释放因子3；磷酸化Ras蛋白特异鸟嘌呤核苷酸释放因子3；

背景信息：

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]