基因名:
EML2
产品别名:
ELP70; EMAP-2; EMAP2; EML2; EMAP like 2; EMAP like 2; echinoderm microtubule-associated protein-like 2; echinoderm MT-associated protein (EMAP)-like protein 70; echinoderm microtubule associated protein like 2; microtubule-associated protein like echinoderm EMAP; EML2蛋白; 棘皮动物微管关联蛋白样蛋白2(EML2);
背景信息:
Microtubules are components of the actin cytoskeleton that play crucial roles in cell morphogenesis, cell motility, spindle formation and chromosome movements. Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules. EML2 (echinoderm microtubule associated protein like 2), also known as ELP70, EMAP2 or EMAPL2, is a cytoplasmic protein that acts to elongate microtubules, while at the same time making them more dynamic. Like other members of the EML family, EML2 contains a hydrophobic ELP (HELP) domain and a large WD repeat domain, both of which allow EML2 to participate in cytoskeleton assembly.