基因名:
LPAR3
产品别名:
EDG7; Edg-7; GPCR; HOFNH30; LP-A3; LPA3; RP4-678I3; LPAR3; lysophosphatidic acid receptor 3; lysophosphatidic acid receptor 3; lysophosphatidic acid receptor 3; LPA receptor 3; LPA receptor EDG7; LPA-3; calcium-mobilizing lysophosphatidic acid receptor LP-A3; endothelial cell differentiation gene 7; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 7; lysophosphatidic acid receptor Edg-7; 溶血磷脂酸受体3(LPAR3); 溶血磷脂酸受体蛋白3/EDG7;
背景信息:
EDG7 is a member of the G protein-coupled receptor family, as well as the EDG family of proteins. This protein functions as a cellular receptor for lysophosphatidic acid and mediates lysophosphatidic acid-evoked calcium mobilization. This receptor couples predominantly to G(q/11) alpha proteins. EDG7 has been reported in human prostate, as well as rodent brain, kidney, lung, placenta, prostate, and testis. ESTs have been isolated from a normal prostate library, as well as cancer libraries of the head/neck, ovary, and thyroid.