基因名:
SEC14L2
产品别名:
C22orf6; SPF; TAP; TAP1; SEC14L2; SEC14 like lipid binding 2; SEC14 like lipid binding 2; SEC14-like protein 2; alpha-tocopherol-associated protein; squalene transfer protein; supernatant protein factor; tocopherol-associated protein 1; SEC14样蛋白2;
背景信息:
Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.
Tissue specificity: Widely expressed. Strong expression in liver, brain and prostate.