基因名：
ZHX2
产品别名：
AFR1； RAF； ZHX2； zinc fingers and homeoboxes 2； zinc fingers and homeoboxes 2； zinc fingers and homeoboxes protein 2； AFP regulator 1； alpha-fetoprotein regulator 1； regulator of AFP； transcription factor ZHX2； zinc finger and homeodomain protein 2； 甲胎蛋白调节蛋白1；
背景信息：
The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. [provided by RefSeq, Jul 2008].[FUNCTION] Acts as a transcriptional repressor.[SUBUNIT] Forms homodimers. Also forms heterodimers with ZHX1 and ZHX3. Heterodimerization with ZHX1 is not necessary for repressor activity. Interacts with NFYA.[SUBCELLULAR LOCATION] Nucleus. [TISSUE SPECIFICITY] Ubiquitously expressed. [SIMILARITY] Belongs to the ZHX family.
