基因名:
ATG14
产品别名:
ATG14L; BARKOR; KIAA0831; ATG14; autophagy related 14; autophagy related 14; beclin 1-associated autophagy-related key regulator; ATG14 autophagy related 14 homolog; Beclin 1-Interacting protein; autophagy-related protein 14-like protein; 自噬相关蛋白14;
背景信息:
Required for both basal and inducible autophagy. Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine. Promotes BECN1 translocation from the trans-Golgi network to autophagosomes. Enhances PIK3C3 activity in a BECN1-dependent manner.