基因名:
Sin3b
产品别名:
2810430C10Rik; Sin3b; transcriptional regulator, SIN3B (yeast); transcriptional regulator, SIN3B (yeast); paired amphipathic helix protein Sin3b; SIN3 homolog B, transcription regulator; histone deacetylase complex subunit Sin3b; transcriptional corepressor Sin3b; transcriptional regulator, SIN3 yeast homolog B; 转录抑制蛋白Sin3b;
背景信息:
Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription.