基因名：
Rasa3
产品别名：
AI326412； C86362； E130011G04； GAPIII； hlb381； scat； Rasa3； RAS p21 protein activator 3； RAS p21 protein activator 3； ras GTPase-activating protein 3； GAP1(IP4BP)； GAPIII activator 3； R-Ras gap； R-ras RTPase activating protein-3； Ras GTPase-activating protein III； ins P4-binding protein； Ras-GTP酶激活蛋白3；
背景信息：
RASA3 is a inhibitory regulator of the Ras-cyclic AMP pathway and is a member of the GAP1 family of GTPase-activating proteins. It stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. RASA3 is an inositol 1,3,4,5-tetrakisphosphate-binding protein (IP4).
