基因名:
Pabpc1
产品别名:
PABP; Pabp1; PabpI; Pabpl1; ePAB; Pabpc1; poly(A) binding protein, cytoplasmic 1; poly(A) binding protein, cytoplasmic 1; polyadenylate-binding protein 1; PABP-1; poly(A)-binding protein 1; 多聚腺苷酸结合蛋白; 甲基化多聚腺苷酸结合蛋白; 胞浆多聚A结合蛋白1(PABPC1);
背景信息:
This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010].