基因名:
Il17ra
产品别名:
AW538159; Cdw217; Il17r; VDw217; Il17ra; interleukin 17 receptor A; interleukin 17 receptor A; interleukin-17 receptor A; IL-17 receptor A; IL-17RA; IL17RA蛋白; 白介素17受体; 白介素17受体A(IL17RA);
背景信息:
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.