基因名:
Cdca3
产品别名:
2410005A12Rik; C8; Grcc8; Tome-1; Cdca3; cell division cycle associated 3; cell division cycle associated 3; cell division cycle-associated protein 3; gene rich cluster, C8; gene-rich cluster protein C8; trigger of mitotic entry 1; trigger of mitotic entry protein 1; 细胞分裂周期相关蛋白3;
背景信息:
CDCA3 (Cell division cycle associated 3) is an F-box-like protein which is required for entry into mitosis. It is associated with SKP1 as part of a SCF (SKP1-cullin-F-box) protein ligase complex, and is required for the ubiquitination and degradation of the CDK1 inhibitory tyrosine kinase WEE1 at G2/M phase.