基因名:
Fkbp7
产品别名:
23kDa; FKBP-7; FKBP23; Fkbp7; FK506 binding protein 7; FK506 binding protein 7; peptidyl-prolyl cis-trans isomerase FKBP7; 23 kDa FK506-binding protein; 23 kDa FKBP; FKBP-23; PPIase FKBP7; rotamase; FK506结合蛋白7(FKBP7); FK506结合蛋白7(FKBP7)真核蛋白; FKBP7蛋白;
背景信息:
Peptidyl-Prolyl Cis-Trans Isomerase FKBP7 (FKBP7) is a member of the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. FKBP7 contains two EF-hand domains and one PPIase FKBP-type domain. FKBP7 exhibits PPIase activity and function as molecular chaperones. In addition, FKBP7 accelerates the folding of proteins during protein synthesis. It has been shown that Hsp90 complex to the nucleus bind its PPIase domain to cytoplasmic dynein, the motor protein responsible for retrograde movement along microtubules.