基因名：
IRAK3
产品别名：
ASRT5； IRAKM； IRAK3； interleukin 1 receptor associated kinase 3； interleukin 1 receptor associated kinase 3； interleukin-1 receptor-associated kinase 3； IL-1 receptor-associated kinase M； inactive IL-1 receptor-associated kinase 3； 白介素1受体关联激酶3(IRAK3)； 白细胞介素1受体相关蛋白激酶M；
背景信息：
This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
