基因名：
INMT
产品别名：
TEMT； INMT； indolethylamine N-methyltransferase； indolethylamine N-methyltransferase； indolethylamine N-methyltransferase； amine N-methyltransferase； aromatic alkylamine N-methyltransferase； arylamine N-methyltransferase； indolamine N-methyltransferase； nicotine N-methyltransferase； thioether S-methyltransferase； 吲哚胺N-甲基转移酶；
背景信息：
Methylation is an important reaction in the metabolism of many drugs, other xenobiotics and endogenous molecules. A methyltransferase is a type of transferase enzyme that transfers a methyl group from a donor to an acceptor. INMT (indolethylamine N-methyltransferase), also known as Temt or aromatic alkylamine N-methyltransferase, is a 264 amino acid protein belonging to the NNMT/PNMT/TEMT family. Localized to the cytoplasm, INMT catalyzes the N-methylation of tryptamine and structurally related compounds. Existing as a monomer, INMT may have a role in the in vivo synthesis of psychoactive compounds or neurotoxins. The gene encoding INMT maps to human chromosome 7p14.3 and mouse chromosome 6 B3.
