基因名：
PTP4A3
产品别名：
PRL-3； PRL-R； PRL3； PTP4A3； protein tyrosine phosphatase 4A3； protein tyrosine phosphatase 4A3； protein tyrosine phosphatase type IVA 3； phosphatase of regenerating liver 3； potentially prenylated protein tyrosine phosphatase； protein tyrosine phosphatase type IVA, member 3； protein-tyrosine phosphatase of regenerating liver 3； 磷酸酯酶3蛋白； 蛋白酪氨酸磷酸酶ⅣA3(PTP4A3)；
背景信息：
PTP4A3 protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. It enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. It may be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. PTP4A3 interacts with tubulin. It belongs to the protein tyrosine phosphatase family. It is mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. It is consistently overexpressed in colon cancer metastasis.
