基因名：
IL1RAPL1
产品别名：
IL-1-RAPL-1； IL-1RAPL-1； IL1R8； IL1RAPL； IL1RAPL-1； MRX10； MRX21； MRX34； OPHN4； TIGIRR-2； IL1RAPL1； interleukin 1 receptor accessory protein like 1； interleukin 1 receptor accessory protein like 1； interleukin-1 receptor accessory protein-like 1； X-linked interleukin-1 receptor accessory protein-like 1； interleukin 1 receptor-8； oligophrenin-4； three immunoglobulin domain-containing IL-1 receptor-related 2； 白介素1受体相关蛋白样1前体蛋白； 白介素1受体辅助蛋白样蛋白1(IL1RAPL1)；
背景信息：
Interleukin-1 receptor accessory protein-like 1, also known as IL1RAPL1, can be detected at low levels in heart, skeletal muscle, ovary, skin, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. IL1RAPL1 functions as a homodimer, it interacts with NCS1, PTPRD. This interaction is PTPRD-splicing-dependent and induces pre- and post-synaptic differentiation of neurons and is required for IL1RAPL1-mediated synapse formation. During dendritic spine formation, it can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD.
