基因名:
CDC37
产品别名:
P50CDC37; CDC37; cell division cycle 37, HSP90 cochaperone; cell division cycle 37, HSP90 cochaperone; hsp90 co-chaperone Cdc37; CDC37 (cell division cycle 37, S. cerevisiae, homolog); CDC37 cell division cycle 37 homolog; cell division cycle 37 homolog; hsp90 chaperone protein kinase-targeting subunit; Hsp90辅助伴侣分子CDC37; 磷酸化细胞分化周期蛋白37;
背景信息:
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]