基因名：
ILVBL
产品别名：
209L8； AHAS； HACL1L； ILV2H； ILVBL； ilvB acetolactate synthase like； ilvB acetolactate synthase like； 2-hydroxyacyl-CoA lyase 2； 2-hydroxyacyl-CoA lyase 1 like； acetolactate synthase homolog； acetolactate synthase-like protein； ilvB (bacterial acetolactate synthase)-like； ilvB-like protein； 乙酰乳酸合成酶蛋白；
背景信息：
ILVBL is a 632 amino acid single-pass membrane protein that belongs to the TPP enzyme family. Expressed in the majority of tissues, ILVBL has the highest level of expression in heart, pancreas and placenta. ILVBL is highly homologous to several bacterial enzymes, including the B isozyme of the large catalytic subunit of E. coli acetohydroxy-acid synthase (AHAS) and the oxalyl-coA decarboxylase of O. formigenes, that utilize thiamine pyrophosphate as a cofactor. ILVBL binds one magnesium ion and one thiamine pyrophosphate per subunit, and may catalyze the initial step in branched-chain amino acid biosynthesis. The gene encoding ILVBL maps to human chromosome 19p13.12 and mouse chromosome 10 C1.
