基因名:
PRDX3
产品别名:
AOP-1; AOP1; HBC189; MER5; PPPCD; PRO1748; SCAR32; SP-22; prx-III; PRDX3; peroxiredoxin 3; peroxiredoxin 3; thioredoxin-dependent peroxide reductase, mitochondrial; antioxidant protein 1; epididymis secretory sperm binding protein; peroxiredoxin III; protein MER5 homolog; thioredoxin-dependent peroxiredoxin 3; 硫氧还蛋白还原酶3; 过氧化还原酶3(PRDX3);
背景信息:
Thioredoxin-Dependent Peroxide Reductase Mitochondrial (PRDX3) is an enzyme that belongs to the AhpC/TSA family. Human and mouse PRDX3 genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Human PRDX3 protein has an antioxidant function and is localized in the mitochondrion. PRDX3 is involved in redox regulation of the cell. PRDX3 protects radical-sensitive enzymes from oxidative damage by a radical-generating system. It acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.