基因名：
MORF4L1
产品别名：
Eaf3； FWP006； HsT17725； MEAF3； MORFRG15； MRG15； S863-6； MORF4L1； mortality factor 4 like 1； mortality factor 4 like 1； mortality factor 4-like protein 1； Esa1p-associated factor 3 homolog； MORF-related gene 15 protein； MORF-related gene on chromosome 15； protein MSL3-1； transcription factor-like protein MRG15； 细胞衰老相关蛋白1； 转录调控因子MRG15；
背景信息：
MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.
