基因名:
FASTK
产品别名:
FAST; FASTK; Fas activated serine/threonine kinase; Fas activated serine/threonine kinase; fas-activated serine/threonine kinase; FAST kinase; Fas活化的丝/苏氨酸激酶; Fas激活丝氨酸/苏氨酸激酶(FASTK);
背景信息:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis promoting nuclear RNA binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full length natures have not yet been determined.