基因名：
JTB
产品别名：
HJTB； HSPC222； PAR； hJT； JTB； jumping translocation breakpoint； jumping translocation breakpoint； protein JTB； jumping translocation breakpoint protein； prostate androgen-regulated protein； 前列腺雄激素调节蛋白；
背景信息：
Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.
