基因名：
LYVE1
产品别名：
CRSBP-1； HAR； LYVE-1； XLKD1； LYVE1； lymphatic vessel endothelial hyaluronan receptor 1； lymphatic vessel endothelial hyaluronan receptor 1； lymphatic vessel endothelial hyaluronic acid receptor 1； cell surface retention sequence binding protein-1； extracellular link domain-containing 1； extracellular link domain-containing protein 1； hyaluronic acid receptor； 淋巴管内皮细胞透明质酸受体1(LYVE1)； 淋巴管内皮透明质酸受体；
背景信息：
Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1 is a single-pass type I membrane protein. LYVE-1 is a CD44 homolog found primarily on lymphatic endothelial cells 1. LYVE-1 mainly expressed in endothelial cells lining lymphatic vessels. While LYVE-1 functions is a Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. LYVE-1 plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). It may act as an hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
