基因名：
ME3
产品别名：
NADP-ME； ME3； malic enzyme 3； malic enzyme 3； NADP-dependent malic enzyme, mitochondrial； malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+))； malic enzyme 3, NADP(+)-dependent, mitochondrial； malic enzyme, NADP+-dependent, mitochondrial； mitochondrial NADP(+)-dependent malic enzyme 3； pyruvic-malic carboxylase； 胞浆苹果酸酶3；
背景信息：
Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
