基因名：
CD300C
产品别名：
CLM-6； CMRF-35； CMRF-35A； CMRF35； CMRF35-A1； CMRF35A； CMRF35A1； IGSF16； LIR； CD300C； CD300c molecule； CD300c molecule； CMRF35-like molecule 6； CD300 antigen-like family member C； CD300c antigen； CMRF35 antigen； CMRF35 leukocyte immunoglobulin-like receptor； CMRF35A leukocyte immunoglobulin-like receptor； immunoglobulin superfamily member 16； 免疫球蛋白超家族成员16； 免疫球蛋白超家族成员16(CD300c)；
背景信息：
CD300C is a single-pass type I membrane protein which belongs to the immunoregulatory signaling (IRS) family. CD300C contains one Ig-like V-type domain and is present on the surface of natural killer cells, granulocytes, most myeloid cells, dendritic cells, and a subpopulation of T and B lymphocytes. The CD300C (CMRF-35A) and CD300A (CMRF-35H) molecules are homologous leukocyte surface proteins. CD300a and CD300C play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300A and CD300C are indistinguishable on the surface of NK cells. The ligand for CD300C is presently unknown.
