基因名：
TXNIP
产品别名：
ARRDC6； EST01027； HHCPA78； THIF； VDUP1； TXNIP； thioredoxin interacting protein； thioredoxin interacting protein； thioredoxin-interacting protein； thioredoxin binding protein 2； upregulated by 1,25-dihydroxyvitamin D-3； vitamin D3 up-regulated protein 1； 硫氧还蛋白互作蛋白(TXNIP)； 硫氧还蛋白结合蛋白2；
背景信息：
TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells (from SwissProt).
