基因名：
BATF
产品别名：
B-ATF； BATF1； SFA-2； SFA2； BATF； basic leucine zipper ATF-like transcription factor； basic leucine zipper ATF-like transcription factor； basic leucine zipper transcriptional factor ATF-like； B-cell-activating transcription factor； SF-HT-activated gene 2 protein； activating transcription factor B； basic leucine zipper transcription factor, ATF-like； B细胞转录激活因子；
背景信息：
B-ATF is a nuclear basic leucine zipper protein that belongs to the AP-1/ATF superfamily of transcription factors. The leucine zipper of B-ATF mediates dimerization with members of the Jun family of proteins. The B-ATF protein does not homodimerize efficiently, but rather forms a heterodimer preferentially with c-Jun. The B-ATF/c-Jun protein complex can interact with DNA containing a consensus binding site for AP-1, suggesting that B-ATF functions as a tissue-specific modulator of the AP-1 transcription complex in human cells. B-ATF also associates with IFP35, a leucine zipper protein that translocates to the nucleus following IFN treatment. The gene encoding B-ATF, also designated SFA-2, is strongly expressed in mature T and B lymphocytes, and is up-regulated after transformation by human T-cell leukemia virus type I.
