基因名：
EIF3M
产品别名：
B5； GA17； PCID1； TANGO7； hfl-B5； EIF3M； eukaryotic translation initiation factor 3 subunit M； eukaryotic translation initiation factor 3 subunit M； eukaryotic translation initiation factor 3 subunit M； B5 receptor； PCI domain containing 1 (herpesvirus entry mediator)； PCI domain-containing protein 1； dendritic cell protein； fetal lung protein B5； transport and golgi organization 7 homolog； PCID1蛋白； 真核翻译起始因子3M(EIF3M)；
背景信息：
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2).
