基因名:
PPIE
产品别名:
CYP-33; CYP33; PPIE; peptidylprolyl isomerase E; peptidylprolyl isomerase E; peptidyl-prolyl cis-trans isomerase E; PPIase E; cyclophilin-33; peptidylprolyl isomerase E (cyclophilin E); rotamase E; 亲环蛋白(亲环素)E; 肽基脯氨酰异构酶E(PPIE);
背景信息:
Peptidyl-prolyl cis-trans isomerase E, also known as Cyclophilin E, Cyclophilin-33, Rotamase E, CYP33, PPIE, is an enzyme which belongs to the cyclophilin-type PPIase family of PPIase E subfamily. PPIE found in all the examined tissues including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. PPIE contains one PPIase cyclophilin-type domain and one RRM (RNA recognition motif) domain. PPIE accelerates the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIE combines RNA-binding and PPIase activities. It may be involved in muscle- and brain-specific processes and pre-mRNA splici