基因名:
DLC1
产品别名:
ARHGAP7; HP; STARD12; p122-RhoGAP; DLC1; DLC1 Rho GTPase activating protein; DLC1 Rho GTPase activating protein; rho GTPase-activating protein 7; Rho-GTPase-activating protein 7; START domain-containing protein 12; StAR-related lipid transfer (START) domain containing 12; deleted in liver cancer 1 protein; epididymis secretory sperm binding protein; rho-type GTPase-activating protein 7; 磷酸化肝癌缺失基因1; 肝癌缺失基因1; 肝癌缺失基因1/2;
背景信息:
This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010]