基因名:
RTN3
产品别名:
ASYIP; HAP; NSPL2; NSPLII; RTN3-A1; RTN3; reticulon 3; reticulon 3; reticulon-3; ASY interacting protein; NSP-like protein 2; NSP-like protein II; homolog of ASY protein; neuroendocrine-specific protein-like 2; neuroendocrine-specific protein-like II; 神经内分泌特异性蛋白2;
背景信息:
May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.