基因名：
BCAS2
产品别名：
DAM1； SPF27； Snt309； BCAS2； BCAS2 pre-mRNA processing factor； BCAS2 pre-mRNA processing factor； pre-mRNA-splicing factor SPF27； DNA amplified in mammary carcinoma 1 protein； breast carcinoma amplified sequence 2； spliceosome associated protein, amplified in breast cancer； spliceosome-associated protein SPF 27； 乳腺癌扩增序列2(BCAS2)； 乳腺癌相关蛋白2；
背景信息：
Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator and is capable of enhancing ER-mediated transcription.
