基因名:
G3BP1
产品别名:
G3BP; HDH-VIII; G3BP1; G3BP stress granule assembly factor 1; G3BP stress granule assembly factor 1; ras GTPase-activating protein-binding protein 1; ATP-dependent DNA helicase VIII; DNA helicase VIII; G3BP-1; GAP SH3 domain-binding protein 1; GAP binding protein; GTPase activating protein (SH3 domain) binding protein 1; Ras-GTPase-activating protein SH3-domain-binding protein; RasGAP-associated endoribonuclease G3BP; Ras GTP酶活化蛋白结合蛋白1; 磷酸化Ras GTP酶活化蛋白结合蛋白1;
背景信息:
This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq].