基因名:
SMC4
产品别名:
CAP-C; CAPC; SMC-4; SMC4L1; SMC4; structural maintenance of chromosomes 4; structural maintenance of chromosomes 4; structural maintenance of chromosomes protein 4; SMC protein 4; SMC4 structural maintenance of chromosomes 4-like 1; chromosome-associated polypeptide C; 染色体结构维持蛋白4;
背景信息:
SMC4 is a central component of the condensin complex, which is required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.