基因名：
DNAJB6
产品别名：
DJ4； DnaJ； HHDJ1； HSJ-2； HSJ2； LGMD1D； LGMD1E； LGMDD1； MRJ； MSJ-1； DNAJB6； DnaJ heat shock protein family (Hsp40) member B6； DnaJ heat shock protein family (Hsp40) member B6； dnaJ homolog subfamily B member 6； DnaJ (Hsp40) homolog, subfamily B, member 6； DnaJ-like 2 protein； heat shock protein J2； 热休克蛋白J2；
背景信息：
Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Reduces huntingtin aggregation associated with HD. Also reduces cellular toxicity and caspase-3 activity.
