基因名:
FGFBP1
产品别名:
FGF-BP; FGF-BP1; FGFBP; FGFBP-1; HBP17; FGFBP1; fibroblast growth factor binding protein 1; fibroblast growth factor binding protein 1; fibroblast growth factor-binding protein 1; 17 kDa HBGF-binding protein; 17 kDa heparin-binding growth factor-binding protein; FGF-binding protein 1; heparin-binding growth factor binding protein; 纤维细胞生长因子结合蛋白;
背景信息:
This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]