基因名：
ARNT2
产品别名：
WEDAS； bHLHe1； ARNT2； aryl hydrocarbon receptor nuclear translocator 2； aryl hydrocarbon receptor nuclear translocator 2； aryl hydrocarbon receptor nuclear translocator 2； ARNT protein 2； class E basic helix-loop-helix protein 1； 芳香烃受体核转位蛋白2(ARNT2)； 芳香烃受体核转录蛋白2；
背景信息：
ARNT2 is a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. It acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, ARNT2 protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes.
